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Genetic Polymorphisms Associated with Vincristine Pharmacokinetics and Vincristine-Induced Peripheral Neuropathy in Pediatric Oncology Patients

SIMPLE SUMMARY: Vincristine is a type of chemotherapy that is often used in the treatment of children with cancer. The main side effect of vincristine is nerve damage. Patients experience symptoms such as tingling, pain or muscle weakness. Some children are more sensitive to vincristine than others,...

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Detalles Bibliográficos
Autores principales: van de Velde, Mirjam E., Uittenboogaard, Aniek, Yang, Wenjian, Bonten, Erik, Cheng, Cheng, Pei, Deqing, van den Berg, Marleen H., van der Sluis, Inge M., van den Bos, Cor, Abbink, Floor C. H., van den Heuvel-Eibrink, Marry M., Segers, Heidi, Chantrain, Christophe, van der Werff ten Bosch, Jutte, Willems, Leen, Evans, William E., Kaspers, Gertjan J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321338/
https://www.ncbi.nlm.nih.gov/pubmed/35884569
http://dx.doi.org/10.3390/cancers14143510