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Genome-wide regulation of KSHV RNA splicing by viral RNA-binding protein ORF57

RNA splicing plays an essential role in the expression of eukaryotic genes. We previously showed that KSHV ORF57 is a viral splicing factor promoting viral lytic gene expression. In this report, we compared the splicing profile of viral RNAs in BCBL-1 cells carrying a wild-type (WT) versus the cells...

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Detalles Bibliográficos
Autores principales: Majerciak, Vladimir, Alvarado-Hernandez, Beatriz, Lobanov, Alexei, Cam, Maggie, Zheng, Zhi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321434/
https://www.ncbi.nlm.nih.gov/pubmed/35834586
http://dx.doi.org/10.1371/journal.ppat.1010311