The Succinate Receptor SUCNR1 Resides at the Endoplasmic Reticulum and Relocates to the Plasma Membrane in Hypoxic Conditions

The GPCR SUCNR1/GPR91 exerts proangiogenesis upon stimulation with the Krebs cycle metabolite succinate. GPCR signaling depends on the surrounding environment and intracellular localization through location bias. Here, we show by microscopy and by cell fractionation that in neurons, SUCNR1 resides a...

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Detalles Bibliográficos
Autores principales: Sanchez, Melanie, Hamel, David, Bajon, Emmanuel, Duhamel, François, Bhosle, Vikrant K., Zhu, Tang, Rivera, Jose Carlos, Dabouz, Rabah, Nadeau-Vallée, Mathieu, Sitaras, Nicholas, Tremblay, David-Étienne, Omri, Samy, Habelrih, Tiffany, Rouget, Raphael, Hou, Xin, Gobeil, Fernand, Joyal, Jean-Sébastien, Sapieha, Przemyslaw, Mitchell, Grant, Ribeiro-Da-Silva, Alfredo, Mohammad Nezhady, Mohammad Ali, Chemtob, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321536/
https://www.ncbi.nlm.nih.gov/pubmed/35883628
http://dx.doi.org/10.3390/cells11142185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321536/
https://www.ncbi.nlm.nih.gov/pubmed/35883628
http://dx.doi.org/10.3390/cells11142185

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