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Role of Dissimilative Pathway of Komagataella phaffii (Pichia pastoris): Formaldehyde Toxicity and Energy Metabolism

Komagataella phaffii (aka Pichia pastoris) is a yeast able to grow in methanol as the sole carbon and energy source. This substrate is converted into formaldehyde, a toxic intermediary that can either be assimilated to biomass or dissimilated to CO(2) through the enzymes formaldehyde dehydrogenase (...

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Detalles Bibliográficos
Autores principales: Berrios, Julio, Theron, Chrispian W., Steels, Sébastien, Ponce, Belén, Velastegui, Edgar, Bustos, Cristina, Altamirano, Claudia, Fickers, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321669/
https://www.ncbi.nlm.nih.gov/pubmed/35889185
http://dx.doi.org/10.3390/microorganisms10071466