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Pharmacokinetics of glucagon after intravenous, intraperitoneal and subcutaneous administration in a pig model

INTRODUCTION: There is increasing scientific evidence to substantiate using low‐dose glucagon as a supplement to insulin therapy in artificial pancreata for diabetes mellitus type 1. The delivery of both these hormones intraperitoneally would mimic normal physiology. However, our knowledge of the ph...

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Detalles Bibliográficos
Autores principales: Teigen, Ingrid Anna, Åm, Marte Kierulf, Carlsen, Sven Magnus, Christiansen, Sverre Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321685/
https://www.ncbi.nlm.nih.gov/pubmed/35416407
http://dx.doi.org/10.1111/bcpt.13731