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The Epigenetic Regulatory Protein CBX2 Promotes mTORC1 Signalling and Inhibits DREAM Complex Activity to Drive Breast Cancer Cell Growth

SIMPLE SUMMARY: Cancer develops due to the expression of genes that promote cell growth and the repression of genes that limit growth. Epigenetics is a mechanism that regulates gene expression via the chemical modification of DNA and histones. Proteins that regulate this process have emerged as pote...

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Detalles Bibliográficos
Autores principales: Bilton, Lucie J., Warren, Chloe, Humphries, Rebecca M., Kalsi, Shannon, Waters, Ella, Francis, Thomas, Dobrowinski, Wojtek, Beltran-Alvarez, Pedro, Wade, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321755/
https://www.ncbi.nlm.nih.gov/pubmed/35884550
http://dx.doi.org/10.3390/cancers14143491