Aluminum hydroxide adjuvant diverts the uptake and trafficking of genetically detoxified pertussis toxin to lysosomes in macrophages

Aluminum salts have been successfully utilized as adjuvants to enhance the immunogenicity of vaccine antigens since the 1930s. However, the cellular mechanisms behind the immune adjuvanticity effect of these materials in antigen‐presenting cells are poorly understood. In this study, we investigated...

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Detalles Bibliográficos
Autores principales: Jaldin‐Fincati, Javier R., Moussaoui, Serene, Gimenez, Maria Cecilia, Ho, Cheuk Y., Lancaster, Charlene E., Botelho, Roberto J., Ausar, Salvador F., Brookes, Roger H., Terebiznik, Mauricio R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321756/
https://www.ncbi.nlm.nih.gov/pubmed/35344242
http://dx.doi.org/10.1111/mmi.14900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321756/
https://www.ncbi.nlm.nih.gov/pubmed/35344242
http://dx.doi.org/10.1111/mmi.14900

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