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Translating questions to estimands in randomized clinical trials with intercurrent events

Intercurrent (post‐treatment) events occur frequently in randomized trials, and investigators often express interest in treatment effects that suitably take account of these events. Contrasts that naively condition on intercurrent events do not have a straight‐forward causal interpretation, and the...

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Detalles Bibliográficos
Autores principales: Stensrud, Mats J., Dukes, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321763/
https://www.ncbi.nlm.nih.gov/pubmed/35578779
http://dx.doi.org/10.1002/sim.9398