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LCMV induced downregulation of HVEM on antiviral T cells is critical for an efficient effector response

T‐cell responses against tumors and pathogens are critically shaped by cosignaling molecules providing a second signal. Interaction of herpes virus entry mediator (HVEM, CD270, TNFRSF14) with multiple ligands has been proposed to promote or inhibit T‐cell responses and inflammation, dependent on the...

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Detalles Bibliográficos
Autores principales: Diethelm, Patrizia, Schmitz, Iwana, Iten, Irina, Kisielow, Jan, Matsushita, Mai, Kopf, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321772/
https://www.ncbi.nlm.nih.gov/pubmed/35344223
http://dx.doi.org/10.1002/eji.202048569