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A specific EMC subunit supports Dengue virus infection by promoting virus membrane fusion essential for cytosolic genome delivery

Dengue virus (DENV) represents the most common human arboviral infection, yet its cellular entry mechanism remains unclear. The multi-subunit endoplasmic reticulum membrane complex (EMC) supports DENV infection, in part, by assisting the biosynthesis of viral proteins critical for downstream replica...

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Detalles Bibliográficos
Autores principales: Bagchi, Parikshit, Speckhart, Kaitlyn, Kennedy, Andrew, Tai, Andrew W., Tsai, Billy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321775/
https://www.ncbi.nlm.nih.gov/pubmed/35834589
http://dx.doi.org/10.1371/journal.ppat.1010717