Macrophage Lysosomal Alkalinization Drives Invasive Aspergillosis in a Mouse Cystic Fibrosis Model of Airway Transplantation

Cystic fibrosis (CF) lung transplant recipients (LTRs) exhibit a disproportionately high rate of life-threatening invasive aspergillosis (IA). Loss of the cystic fibrosis transmembrane conductance regulator (CFTR(-/-)) in macrophages (mφs) has been associated with lyosomal alkalinization. We hypothe...

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Detalles Bibliográficos
Autores principales: Matthaiou, Efthymia Iliana, Chiu, Wayland, Conrad, Carol, Hsu, Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321820/
https://www.ncbi.nlm.nih.gov/pubmed/35887506
http://dx.doi.org/10.3390/jof8070751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321820/
https://www.ncbi.nlm.nih.gov/pubmed/35887506
http://dx.doi.org/10.3390/jof8070751

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