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Unravelling the tumour genome: The evolutionary and clinical impacts of structural variants in tumourigenesis
Structural variants (SVs) represent a major source of aberration in tumour genomes. Given the diversity in the size and type of SVs present in tumours, the accurate detection and interpretation of SVs in tumours is challenging. New classes of complex structural events in tumours are discovered frequ...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321913/ https://www.ncbi.nlm.nih.gov/pubmed/35355264 http://dx.doi.org/10.1002/path.5901 |