New N-Alkylated Heterocyclic Compounds as Prospective NDM1 Inhibitors: Investigation of In Vitro and In Silico Properties

A new family of pyrazole-based compounds (1–15) was synthesized and characterized using different physicochemical analyses, such as FTIR, UV-Visible, (1)H, (13)C NMR, and ESI/LC-MS. The compounds were evaluated for their in vitro antifungal and antibacterial activities against several fungal and bac...

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Detalles Bibliográficos
Autores principales: Kaddouri, Yassine, Bouchal, Btissam, Abrigach, Farid, El Kodadi, Mohamed, Bellaoui, Mohammed, Elkamhawy, Ahmed, Touzani, Rachid, Abdellattif, Magda H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322059/
https://www.ncbi.nlm.nih.gov/pubmed/35890102
http://dx.doi.org/10.3390/ph15070803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322059/
https://www.ncbi.nlm.nih.gov/pubmed/35890102
http://dx.doi.org/10.3390/ph15070803

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