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Melatonin Prevents UVB-Induced Skin Photoaging by Inhibiting Oxidative Damage and MMP Expression through JNK/AP-1 Signaling Pathway in Human Dermal Fibroblasts

Exposure to ultraviolet (UV) irradiation causes damage to the skin and induces photoaging. UV irradiation stimulates production of reactive oxygen/nitrogen species, which results in activation of epidermal growth factor receptor (EGFR) and mitogen-activated protein kinases (MAPK) in fibroblasts. MAP...

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Detalles Bibliográficos
Autores principales: Yuksel Egrilmez, Mehtap, Kocturk, Semra, Aktan, Sebnem, Oktay, Gulgun, Resmi, Halil, Simsek Keskin, Hatice, Guner Akdogan, Gul, Ozkan, Sebnem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322074/
https://www.ncbi.nlm.nih.gov/pubmed/35888040
http://dx.doi.org/10.3390/life12070950