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Discovering Tuberosin and Villosol as Potent and Selective Inhibitors of AKT1 for Therapeutic Targeting of Oral Squamous Cell Carcinoma

Oral squamous cell carcinoma (OSCC) is a major cause of death in developing countries because of high tobacco consumption. RAC-alpha serine-threonine kinase (AKT1) is considered as an attractive drug target because its prolonged activation and overexpression are associated with cancer progression an...

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Detalles Bibliográficos
Autores principales: Adnan, Mohd, Jairajpuri, Deeba Shamim, Chaddha, Muskan, Khan, Mohd Shahnawaz, Yadav, Dharmendra Kumar, Mohammad, Taj, Elasbali, Abdelbaset Mohamed, Abu Al-Soud, Waleed, Hussain Alharethi, Salem, Hassan, Md. Imtaiyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322152/
https://www.ncbi.nlm.nih.gov/pubmed/35887580
http://dx.doi.org/10.3390/jpm12071083