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Discovering Tuberosin and Villosol as Potent and Selective Inhibitors of AKT1 for Therapeutic Targeting of Oral Squamous Cell Carcinoma
Oral squamous cell carcinoma (OSCC) is a major cause of death in developing countries because of high tobacco consumption. RAC-alpha serine-threonine kinase (AKT1) is considered as an attractive drug target because its prolonged activation and overexpression are associated with cancer progression an...
Autores principales: | Adnan, Mohd, Jairajpuri, Deeba Shamim, Chaddha, Muskan, Khan, Mohd Shahnawaz, Yadav, Dharmendra Kumar, Mohammad, Taj, Elasbali, Abdelbaset Mohamed, Abu Al-Soud, Waleed, Hussain Alharethi, Salem, Hassan, Md. Imtaiyaz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322152/ https://www.ncbi.nlm.nih.gov/pubmed/35887580 http://dx.doi.org/10.3390/jpm12071083 |
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