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Continuous countercurrent chromatographic twin‐column purification of oligonucleotides: The role of the displacement effect
Oligonucleotides (ONs) are breaking through in the biopharmaceutical industry as a promising class of biotherapeutics. The main success of these molecules is due to their peculiar way of acting in the cellular process, regulating the gene expression and hence influencing the protein synthesis at a p...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322279/ https://www.ncbi.nlm.nih.gov/pubmed/35338661 http://dx.doi.org/10.1002/bit.28093 |