Photoactivatable V‐Shaped Bifunctional Quinone Methide Precursors as a New Class of Selective G‐quadruplex Alkylating Agents

Combining the selectivity of G‐quadruplex (G4) ligands with the spatial and temporal control of photochemistry is an emerging strategy to elucidate the biological relevance of these structures. In this work, we developed six novel V‐shaped G4 ligands that can, upon irradiation, form stable covalent...

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Detalles Bibliográficos
Autores principales: Lena, Alberto, Benassi, Alessandra, Stasi, Michele, Saint‐Pierre, Christine, Freccero, Mauro, Gasparutto, Didier, Bombard, Sophie, Doria, Filippo, Verga, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322314/
https://www.ncbi.nlm.nih.gov/pubmed/35441438
http://dx.doi.org/10.1002/chem.202200734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322314/
https://www.ncbi.nlm.nih.gov/pubmed/35441438
http://dx.doi.org/10.1002/chem.202200734

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