Enzyme‐Activated, Chemiluminescent Siderophore‐Dioxetane Probes Enable the Selective and Highly Sensitive Detection of Bacterial Pathogens

The sensitive detection of bacterial infections is a prerequisite for their successful treatment. The use of a chemiluminescent readout was so far hampered by an insufficient probe enrichment at the pathogens. We coupled siderophore moieties, that harness the unique iron transport system of bacteria...

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Detalles Bibliográficos
Autores principales: Peukert, Carsten, Popat Gholap, Sachin, Green, Ori, Pinkert, Lukas, van den Heuvel, Joop, van Ham, Marco, Shabat, Doron, Brönstrup, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322335/
https://www.ncbi.nlm.nih.gov/pubmed/35358362
http://dx.doi.org/10.1002/anie.202201423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322335/
https://www.ncbi.nlm.nih.gov/pubmed/35358362
http://dx.doi.org/10.1002/anie.202201423

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