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Enzyme‐Activated, Chemiluminescent Siderophore‐Dioxetane Probes Enable the Selective and Highly Sensitive Detection of Bacterial Pathogens
The sensitive detection of bacterial infections is a prerequisite for their successful treatment. The use of a chemiluminescent readout was so far hampered by an insufficient probe enrichment at the pathogens. We coupled siderophore moieties, that harness the unique iron transport system of bacteria...
Autores principales: | Peukert, Carsten, Popat Gholap, Sachin, Green, Ori, Pinkert, Lukas, van den Heuvel, Joop, van Ham, Marco, Shabat, Doron, Brönstrup, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322335/ https://www.ncbi.nlm.nih.gov/pubmed/35358362 http://dx.doi.org/10.1002/anie.202201423 |
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