The Impact of CYP2C9*11 Allelic Variant on the Pharmacokinetics of Phenytoin and (S)‐Warfarin

Cytochrome P450 2C9 (CYP2C9) is responsible for the oxidative metabolism of about 15% of commonly used drugs, some of which are characterized by a narrow therapeutic window. CYP2C9 is highly polymorphic, and over 60 alleles have been described. CYP2C9*2 and CYP2C9*3 are the most common polymorphisms...

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Detalles Bibliográficos
Autores principales: Wanounou, Maor, Shaul, Chanan, Abu Ghosh, Zahi, Alamia, Shoshana, Caraco, Yoseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322346/
https://www.ncbi.nlm.nih.gov/pubmed/35426132
http://dx.doi.org/10.1002/cpt.2613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322346/
https://www.ncbi.nlm.nih.gov/pubmed/35426132
http://dx.doi.org/10.1002/cpt.2613

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