Dawn and dusk peaks of outer segment phagocytosis, and visual cycle function require Rab28

RAB28 is a farnesylated, ciliary G‐protein. Patient variants in RAB28 are causative of autosomal recessive cone‐rod dystrophy (CRD), an inherited human blindness. In rodent and zebrafish models, the absence of Rab28 results in diminished dawn, photoreceptor, outer segment phagocytosis (OSP). Here, w...

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Detalles Bibliográficos
Autores principales: Moran, Ailís L., Carter, Stephen P., Kaylor, Joanna J., Jiang, Zhichun, Broekman, Sanne, Dillon, Eugene T., Gómez Sánchez, Alicia, Minhas, Sajal K., van Wijk, Erwin, Radu, Roxana A., Travis, Gabriel H., Carey, Michelle, Blacque, Oliver E., Kennedy, Breandán N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322422/
https://www.ncbi.nlm.nih.gov/pubmed/35471581
http://dx.doi.org/10.1096/fj.202101897R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322422/
https://www.ncbi.nlm.nih.gov/pubmed/35471581
http://dx.doi.org/10.1096/fj.202101897R

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