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Endothelin‐1 dependent expression of GAG genes involves NOX and p38 mediated Smad linker region phosphorylation

Endothelin‐1 (ET‐1) is implicated in the development of atherosclerosis and mediates glycosaminoglycan (GAG) chain hyperelongation on proteoglycans. Our aim was to identify the ET‐1‐mediated signalling pathway involving NADPH oxidase (NOX), p38 MAP kinsae and Smad2 linker region phosphorylation (pho...

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Detalles Bibliográficos
Autores principales: Babaahmadi‐Rezaei, Hossein, Mohamed, Raafat, Dayati, Parisa, Mehr, Reyhaneh Niayesh, Seif, Faezeh, Sharifat, Narges, Khedri, Azam, Kamato, Danielle, Little, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322435/
https://www.ncbi.nlm.nih.gov/pubmed/35527471
http://dx.doi.org/10.1111/1440-1681.13650