AOP report: Development of an adverse outcome pathway for oxidative DNA damage leading to mutations and chromosomal aberrations

The Genetic Toxicology Technical Committee (GTTC) of the Health and Environmental Sciences Institute (HESI) is developing adverse outcome pathways (AOPs) that describe modes of action leading to potentially heritable genomic damage. The goal was to enhance the use of mechanistic information in genot...

Descripción completa

Detalles Bibliográficos
Autores principales: Cho, Eunnara, Allemang, Ashley, Audebert, Marc, Chauhan, Vinita, Dertinger, Stephen, Hendriks, Giel, Luijten, Mirjam, Marchetti, Francesco, Minocherhomji, Sheroy, Pfuhler, Stefan, Roberts, Daniel J., Trenz, Kristina, Yauk, Carole L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322445/
https://www.ncbi.nlm.nih.gov/pubmed/35315142
http://dx.doi.org/10.1002/em.22479