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AOP report: Development of an adverse outcome pathway for oxidative DNA damage leading to mutations and chromosomal aberrations
The Genetic Toxicology Technical Committee (GTTC) of the Health and Environmental Sciences Institute (HESI) is developing adverse outcome pathways (AOPs) that describe modes of action leading to potentially heritable genomic damage. The goal was to enhance the use of mechanistic information in genot...
Autores principales: | Cho, Eunnara, Allemang, Ashley, Audebert, Marc, Chauhan, Vinita, Dertinger, Stephen, Hendriks, Giel, Luijten, Mirjam, Marchetti, Francesco, Minocherhomji, Sheroy, Pfuhler, Stefan, Roberts, Daniel J., Trenz, Kristina, Yauk, Carole L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322445/ https://www.ncbi.nlm.nih.gov/pubmed/35315142 http://dx.doi.org/10.1002/em.22479 |
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