Broadly Applicable, Virus-Free Dual Reporter Assay to Identify Compounds Interfering with Membrane Fusion: Performance for HSV-1 and SARS-CoV-2

Membrane fusion constitutes an essential step in the replication cycle of numerous viral pathogens, hence it represents an important druggable target. In the present study, we established a virus-free, stable reporter fusion inhibition assay (SRFIA) specifically designed to identify compounds interf...

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Detalles Bibliográficos
Autores principales: Classen, Nica, Ulrich, Diana, Hofemeier, Arne, Hennies, Marc Tim, Hafezi, Wali, Pettke, Aleksandra, Romberg, Marie-Luise, Lorentzen, Eva U., Hensel, Andreas, Kühn, Joachim E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322530/
https://www.ncbi.nlm.nih.gov/pubmed/35891336
http://dx.doi.org/10.3390/v14071354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322530/
https://www.ncbi.nlm.nih.gov/pubmed/35891336
http://dx.doi.org/10.3390/v14071354

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