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Selective ablation of Nfix in macrophages attenuates muscular dystrophy by inhibiting fibro‐adipogenic progenitor‐dependent fibrosis

Muscular dystrophies are genetic diseases characterized by chronic inflammation and fibrosis. Macrophages are immune cells that sustain muscle regeneration upon acute injury but seem deleterious in the context of chronic muscle injury such as in muscular dystrophies. Here, we observed that the numbe...

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Detalles Bibliográficos
Autores principales: Saclier, Marielle, Angelini, Giuseppe, Bonfanti, Chiara, Mura, Giada, Temponi, Giulia, Messina, Graziella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322546/
https://www.ncbi.nlm.nih.gov/pubmed/35297529
http://dx.doi.org/10.1002/path.5895