DNA Methylation by Bisulfite Next-Generation Sequencing for MLH1 and MGMT in Oral Squamous Cell Carcinomas and Potentially Malignant Disorders: An Integrative Analysis towards Field Cancerization

Background and Objectives: MGMT methylation is a well-described biomarker in several solid tumors and MLH1 seems to occur in the initial stages of oral carcinogenesis. The aims of this study were to evaluate MHL1 and MGMT methylation levels in oral squamous cell carcinoma (OSCC) and oral potentially...

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Detalles Bibliográficos
Autores principales: Padin-Iruegas, Elena, Chamorro-Petronacci, Cintia M., Sines-Cajade, Iria, Lorenzo-Pouso, Alejandro I., Blanco-Carrión, Andrés, Pérez-Jardón, Alba, Gándara-Vila, Pilar, Pérez-Sayans, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322644/
https://www.ncbi.nlm.nih.gov/pubmed/35888599
http://dx.doi.org/10.3390/medicina58070878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322644/
https://www.ncbi.nlm.nih.gov/pubmed/35888599
http://dx.doi.org/10.3390/medicina58070878

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