From Rate-Limiting Enzyme to Therapeutic Target: The Promise of NAMPT in Neurodegenerative Diseases

Nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme in the nicotinamide adenine dinucleotide (NAD) salvage pathway in mammals. It is of great significance in the metabolic homeostasis and cell survival via synthesizing nicotinamide mononucleotide (NMN) through enzymatic activi...

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Detalles Bibliográficos
Autores principales: Zhu, Yumeng, Xu, Ping, Huang, Xuan, Shuai, Wen, Liu, Li, Zhang, Shuai, Zhao, Rui, Hu, Xiuying, Wang, Guan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322656/
https://www.ncbi.nlm.nih.gov/pubmed/35903330
http://dx.doi.org/10.3389/fphar.2022.920113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322656/
https://www.ncbi.nlm.nih.gov/pubmed/35903330
http://dx.doi.org/10.3389/fphar.2022.920113

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