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Sequential Allylic Alcohol Formation by a Multifunctional Cytochrome P450 Monooxygenase with Rare Redox Partners

Caryoynencin is a toxic and antifungal fatty acid derivative produced by a number of plant‐pathogenic and insect‐protective bacteria (Trinickia caryophylli and Burkholderia spp.). In addition to the reactive tetrayne unit, the presence of an allylic alcohol moiety is critical for antimicrobial activ...

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Detalles Bibliográficos
Autores principales: Kim, Hak Joong, Ishida, Keishi, Ishida‐Ito, Mie, Hertweck, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322674/
https://www.ncbi.nlm.nih.gov/pubmed/35416382
http://dx.doi.org/10.1002/anie.202203264