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Streptococcus pyogenes NAD+-Glycohydrolase Reduces Skeletal Muscle βNAD+ Levels Independently of Streptolysin O

Necrotizing soft tissue infections caused by Streptococcus pyogenes (group A streptococcus [GAS]) are characterized by rapid and extensive necrosis of fascia and muscle. Molecular epidemiological studies have demonstrated a positive correlation between GAS isolates that cause invasive infections and...

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Detalles Bibliográficos
Autores principales: McIndoo, Eric R., Price, Emily, Lamb, Cheri L., Dayton, Christopher S., Bayer, Clifford R., Stevens, Dennis L., Bryant, Amy E., Hobdey, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322677/
https://www.ncbi.nlm.nih.gov/pubmed/35889195
http://dx.doi.org/10.3390/microorganisms10071476