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Drug Discovery Using Evolutionary Similarities in Chemical Binding to Inhibit Patient-Derived Hepatocellular Carcinoma

Drug resistance causes therapeutic failure in refractory cancer. Cancer drug resistance stems from various factors, such as patient heterogeneity and genetic alterations in somatic cancer cells, including those from identical tissues. Generally, resistance is intrinsic for cancers; however, cancer r...

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Detalles Bibliográficos
Autores principales: Lim, Jin Hong, Park, Keunwan, Choi, Kyung Hwa, Kim, Chan Wung, Lee, Jae Ha, Weicker, Raymond, Pan, Cheol-Ho, Kim, Seok-Mo, Park, Ki Cheong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322808/
https://www.ncbi.nlm.nih.gov/pubmed/35887321
http://dx.doi.org/10.3390/ijms23147971