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Genetic Architecture of Untargeted Lipidomics in Cardiometabolic-Disease Patients Combines Strong Polygenic Control and Pleiotropy

Analysis of the genetic control of small metabolites provides powerful information on the regulation of the endpoints of genome expression. We carried out untargeted liquid chromatography–high-resolution mass spectrometry in 273 individuals characterized for pathophysiological elements of the cardio...

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Detalles Bibliográficos
Autores principales: Brial, Francois, Hedjazi, Lyamine, Sonomura, Kazuhiro, Al Hageh, Cynthia, Zalloua, Pierre, Matsuda, Fumihiko, Gauguier, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322850/
https://www.ncbi.nlm.nih.gov/pubmed/35888720
http://dx.doi.org/10.3390/metabo12070596