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Genetic Architecture of Untargeted Lipidomics in Cardiometabolic-Disease Patients Combines Strong Polygenic Control and Pleiotropy
Analysis of the genetic control of small metabolites provides powerful information on the regulation of the endpoints of genome expression. We carried out untargeted liquid chromatography–high-resolution mass spectrometry in 273 individuals characterized for pathophysiological elements of the cardio...
Autores principales: | Brial, Francois, Hedjazi, Lyamine, Sonomura, Kazuhiro, Al Hageh, Cynthia, Zalloua, Pierre, Matsuda, Fumihiko, Gauguier, Dominique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322850/ https://www.ncbi.nlm.nih.gov/pubmed/35888720 http://dx.doi.org/10.3390/metabo12070596 |
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