Cargando…
The Future of Tissue-Targeted Lipid Nanoparticle-Mediated Nucleic Acid Delivery
The earliest example of in vivo expression of exogenous mRNA is by direct intramuscular injection in mice without the aid of a delivery vehicle. The current state of the art for therapeutic nucleic acid delivery is lipid nanoparticles (LNP), which are composed of cholesterol, a helper lipid, a PEGyl...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322927/ https://www.ncbi.nlm.nih.gov/pubmed/35890195 http://dx.doi.org/10.3390/ph15070897 |