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The Future of Tissue-Targeted Lipid Nanoparticle-Mediated Nucleic Acid Delivery
The earliest example of in vivo expression of exogenous mRNA is by direct intramuscular injection in mice without the aid of a delivery vehicle. The current state of the art for therapeutic nucleic acid delivery is lipid nanoparticles (LNP), which are composed of cholesterol, a helper lipid, a PEGyl...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322927/ https://www.ncbi.nlm.nih.gov/pubmed/35890195 http://dx.doi.org/10.3390/ph15070897 |