Study on the Mechanism of Mesaconitine-Induced Hepatotoxicity in Rats Based on Metabonomics and Toxicology Network

Mesaconitine (MA), one of the main diterpenoid alkaloids in Aconitum, has a variety of pharmacological effects, such as analgesia, anti-inflammation and relaxation of rat aorta. However, MA is a highly toxic ingredient. At present, studies on its toxicity are mainly focused on the heart and central...

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Detalles Bibliográficos
Autores principales: Chen, Qian, Zhang, Kai, Jiao, Mingjie, Jiao, Jiakang, Chen, Dongling, Yin, Yihui, Zhang, Jia, Li, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322933/
https://www.ncbi.nlm.nih.gov/pubmed/35878224
http://dx.doi.org/10.3390/toxins14070486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322933/
https://www.ncbi.nlm.nih.gov/pubmed/35878224
http://dx.doi.org/10.3390/toxins14070486

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