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Sequence-Specific Features of Short Double-Strand, Blunt-End RNAs Have RIG-I- and Type 1 Interferon-Dependent or -Independent Anti-Viral Effects

Pathogen-associated molecular patterns, including cytoplasmic DNA and double-strand (ds)RNA trigger the induction of interferon (IFN) and antiviral states protecting cells and organisms from pathogens. Here we discovered that the transfection of human airway cell lines or non-transformed fibroblasts...

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Detalles Bibliográficos
Autores principales: Kannan, Abhilash, Suomalainen, Maarit, Volle, Romain, Bauer, Michael, Amsler, Marco, Trinh, Hung V., Vavassori, Stefano, Schmid, Jana Pachlopnik, Vilhena, Guilherme, Marín-González, Alberto, Perez, Ruben, Franceschini, Andrea, von Mering, Christian, Hemmi, Silvio, Greber, Urs F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322957/
https://www.ncbi.nlm.nih.gov/pubmed/35891387
http://dx.doi.org/10.3390/v14071407