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Integrin Signaling Shaping BTK-Inhibitor Resistance

Integrins are adhesion molecules that function as anchors in retaining tumor cells in supportive tissues and facilitating metastasis. Beta1 integrins are known to contribute to cell adhesion-mediated drug resistance in cancer. Very late antigen-4 (VLA-4), a CD49d/CD29 heterodimer, is a beta1 integri...

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Detalles Bibliográficos
Autores principales: Polcik, Laura, Dannewitz Prosseda, Svenja, Pozzo, Federico, Zucchetto, Antonella, Gattei, Valter, Hartmann, Tanja Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9322986/
https://www.ncbi.nlm.nih.gov/pubmed/35883678
http://dx.doi.org/10.3390/cells11142235