HIF-1α induces glycolytic reprograming in tissue-resident alveolar macrophages to promote cell survival during acute lung injury

Cellular metabolism is a critical regulator of macrophage effector function. Tissue-resident alveolar macrophages (TR-AMs) inhabit a unique niche marked by high oxygen and low glucose. We have recently shown that in contrast to bone marrow-derived macrophages (BMDMs), TR-AMs do not utilize glycolysi...

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Detalles Bibliográficos
Autores principales: Woods, Parker S, Kimmig, Lucas M, Sun, Kaitlyn A, Meliton, Angelo Y, Shamaa, Obada R, Tian, Yufeng, Cetin-Atalay, Rengül, Sharp, Willard W, Hamanaka, Robert B, Mutlu, Gökhan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323005/
https://www.ncbi.nlm.nih.gov/pubmed/35822617
http://dx.doi.org/10.7554/eLife.77457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323005/
https://www.ncbi.nlm.nih.gov/pubmed/35822617
http://dx.doi.org/10.7554/eLife.77457

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