Comprehensive fitness landscape of SARS-CoV-2 M(pro) reveals insights into viral resistance mechanisms

With the continual evolution of new strains of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that are more virulent, transmissible, and able to evade current vaccines, there is an urgent need for effective anti-viral drugs. The SARS-CoV-2 main protease (M(pro)) is a leading target for...

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Detalles Bibliográficos
Autores principales: Flynn, Julia M, Samant, Neha, Schneider-Nachum, Gily, Barkan, David T, Yilmaz, Nese Kurt, Schiffer, Celia A, Moquin, Stephanie A, Dovala, Dustin, Bolon, Daniel NA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323007/
https://www.ncbi.nlm.nih.gov/pubmed/35723575
http://dx.doi.org/10.7554/eLife.77433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323007/
https://www.ncbi.nlm.nih.gov/pubmed/35723575
http://dx.doi.org/10.7554/eLife.77433

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