Bilirubin inhibits lipid raft dependent functions of L1 cell adhesion molecule in rat pup cerebellar granule neurons

BACKGROUND: The mechanism of bilirubin neurotoxicity is poorly understood. We hypothesize that bilirubin inhibits the function of lipid rafts (LR), microdomains of the plasma membrane critical for signal transduction. To test this hypothesis, we measured the effect of free bilirubin (Bf) between 7.6...

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Detalles Bibliográficos
Autores principales: Kitchen, Spencer T., Tang, Ningfeng, He, Min, Ly, Eric, Mooney, Sandra M., Bearer, Cynthia F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323028/
https://www.ncbi.nlm.nih.gov/pubmed/32937649
http://dx.doi.org/10.1038/s41390-020-01156-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323028/
https://www.ncbi.nlm.nih.gov/pubmed/32937649
http://dx.doi.org/10.1038/s41390-020-01156-0

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