Cargando…

Bilirubin inhibits lipid raft dependent functions of L1 cell adhesion molecule in rat pup cerebellar granule neurons

BACKGROUND: The mechanism of bilirubin neurotoxicity is poorly understood. We hypothesize that bilirubin inhibits the function of lipid rafts (LR), microdomains of the plasma membrane critical for signal transduction. To test this hypothesis, we measured the effect of free bilirubin (Bf) between 7.6...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kitchen, Spencer T., Tang, Ningfeng, He, Min, Ly, Eric, Mooney, Sandra M., Bearer, Cynthia F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323028/ https://www.ncbi.nlm.nih.gov/pubmed/32937649 http://dx.doi.org/10.1038/s41390-020-01156-0

Ejemplares similares

Neonatal Hypoxia Ischemia Redistributes L1 Cell Adhesion Molecule into Rat Cerebellar Lipid Rafts
por: Waddell, Jaylyn, et al.
Publicado: (2022)

Choline supplementation prevents the effects of bilirubin on cerebellar mediated behavior in choline-restricted Gunn rat pups.
por: Waddell, Jaylyn, et al.
Publicado: (2020)

TOLUENE DISRUPTION OF THE FUNCTIONS OF L1 CELL ADHESION MOLECULE AT CONCENTRATIONS ASSOCIATED WITH OCCUPATIONAL EXPOSURES
por: White, Kimberly M.R., et al.
Publicado: (2016)

Binding of Amyloid β(1–42)-Calmodulin Complexes to Plasma Membrane Lipid Rafts in Cerebellar Granule Neurons Alters Resting Cytosolic Calcium Homeostasis
por: Poejo, Joana, et al.
Publicado: (2021)

The Regulatory Roles of Cerebellar Glycosphingolipid Microdomains/Lipid Rafts
por: Komatsuya, Keisuke, et al.
Publicado: (2023)

The Role of Lipid Rafts in Cancer Cell Adhesion and Migration
por: Murai, Toshiyuki
Publicado: (2012)

Overlapping functions of the cell adhesion molecules Nr-CAM and L1 in cerebellar granule cell development
por: Sakurai, Takeshi, et al.
Publicado: (2001)

Regulation of cerebellar network development by granule cells and their molecules
por: Kim, Muwoong, et al.
Publicado: (2023)

Mechanisms of Amyloid-Beta Peptide Uptake by Neurons: The Role of Lipid Rafts and Lipid Raft-Associated Proteins
por: Lai, Aaron Y., et al.
Publicado: (2010)

Involvement of lipid rafts in adhesion-induced activation of Met and EGFR
por: Lu, Ying-Che, et al.
Publicado: (2011)

Leading-process actomyosin coordinates organelle positioning and adhesion receptor dynamics in radially migrating cerebellar granule neurons
por: Trivedi, Niraj, et al.
Publicado: (2014)

Rac-deficient cerebellar granule neurons die before they migrate to the internal granule layer
por: Katayama, Kei-ichi, et al.
Publicado: (2022)

Presence of Androgen Receptor Variant in Neuronal Lipid Rafts
por: Garza-Contreras, Jo, et al.
Publicado: (2017)

Intermolecular interaction of phosphatidylinositol with the lipid raft molecules sphingomyelin and cholesterol
por: Kinoshita, Masanao, et al.
Publicado: (2008)

Effect of Lipid Raft Disruption on Ethanol Inhibition of L1 Adhesion
por: Dou, Xiaowei, et al.
Publicado: (2014)

Neuronal Signaling Involved in Neuronal Polarization and Growth: Lipid Rafts and Phosphorylation
por: Igarashi, Michihiro, et al.
Publicado: (2020)

RaftProt: mammalian lipid raft proteome database
por: Shah, Anup, et al.
Publicado: (2014)

Cadherin-2 Controls Directional Chain Migration of Cerebellar Granule Neurons
por: Rieger, Sandra, et al.
Publicado: (2009)

Cerebellar granule neuron progenitors are the source of Hk2 in the postnatal cerebellum
por: Gershon, Timothy R, et al.
Publicado: (2013)

PACT/RAX Regulates the Migration of Cerebellar Granule Neurons in the Developing Cerebellum
por: Yong, Yue, et al.
Publicado: (2015)

Isolation and Culture of Post-Natal Mouse Cerebellar Granule Neuron Progenitor Cells and Neurons
por: Lee, Hae Young, et al.
Publicado: (2009)

A GUNN RAT MODEL OF PRETERM HYPERBILIRUBINEMIA
por: Waddell, Jaylyn, et al.
Publicado: (2019)

Bilirubin acts as an endogenous regulator of inflammation by disrupting adhesion molecule-mediated leukocyte migration
por: Vogel, Megan E., et al.
Publicado: (2016)

Localization of the Adhesion Receptor Glycoprotein Ib-IX-V Complex to Lipid Rafts Is Required for Platelet Adhesion and Activation
por: Shrimpton, Corie N., et al.
Publicado: (2002)

Effects of integrin-mediated cell adhesion on plasma membrane lipid raft components and signaling
por: Norambuena, Andrés, et al.
Publicado: (2011)

Characterization of 125I-tissue plasminogen activator binding to cerebellar granule neurons
Publicado: (1989)

Plexin-B2 controls the timing of differentiation and the motility of cerebellar granule neurons
por: Van Battum, Eljo, et al.
Publicado: (2021)

Lipid raft idea is floated
por: Powell, Kendall
Publicado: (2006)

Lipid rafts get connected
por: Leslie, Mitch
Publicado: (2009)

A lifeline for lipid rafts?
por: Leslie, Mitch
Publicado: (2013)

Lipid Rafts and Plant Gravisensitivity
por: Kordyum, Elizabeth L., et al.
Publicado: (2022)

HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains
por: Ren, Tong, et al.
Publicado: (2013)

Human herpesvirus 6 envelope components enriched in lipid rafts: evidence for virion-associated lipid rafts
por: Kawabata, Akiko, et al.
Publicado: (2009)

Age-dependent pattern of cerebellar susceptibility to bilirubin neurotoxicity in vivo in mice
por: Bortolussi, Giulia, et al.
Publicado: (2014)

Transcriptional Analysis of Apoptotic Cerebellar Granule Neurons Following Rescue by Gastric Inhibitory Polypeptide
por: Maino, Barbara, et al.
Publicado: (2014)

ROS Produced by NOX2 Controls In Vitro Development of Cerebellar Granule Neurons Development
por: Olguín-Albuerne, Mauricio, et al.
Publicado: (2015)

Population-scale organization of cerebellar granule neuron signaling during a visuomotor behavior
por: Sylvester, Sherika J. G., et al.
Publicado: (2017)

Neuroprotection Comparison of Rosmarinic Acid and Carnosic Acid in Primary Cultures of Cerebellar Granule Neurons
por: Taram, Faten, et al.
Publicado: (2018)

Optimization of Efficient Neuron Models With Realistic Firing Dynamics. The Case of the Cerebellar Granule Cell
por: Marín, Milagros, et al.
Publicado: (2020)

On the Use of a Multimodal Optimizer for Fitting Neuron Models. Application to the Cerebellar Granule Cell
por: Marín, Milagros, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4bou8e1clen6fqfh9sv9jeigoj