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Smad8 Is Increased in Duchenne Muscular Dystrophy and Suppresses miR-1, miR-133a, and miR-133b

Duchenne muscular dystrophy (DMD) is an X-linked recessive disease characterized by skeletal muscle instability, progressive muscle wasting, and fibrosis. A major driver of DMD pathology stems from aberrant upregulation of transforming growth factor β (TGFβ) signaling. In this report, we investigate...

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Detalles Bibliográficos
Autores principales: Lopez, Michael A., Si, Ying, Hu, Xianzhen, Williams, Valentyna, Qushair, Fuad, Carlyle, Jackson, Alesce, Lyndsy, Conklin, Michael, Gilbert, Shawn, Bamman, Marcas M., Alexander, Matthew S., King, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323105/
https://www.ncbi.nlm.nih.gov/pubmed/35886863
http://dx.doi.org/10.3390/ijms23147515