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Prediction of Response to Cisplatin-Based Neoadjuvant Chemotherapy of Muscle-Invasive Bladder Cancer Patients by Molecular Subtyping including KRT and FGFR Target Gene Assessment

Patients with muscle-invasive urothelial carcinoma achieving pathological complete response (pCR) upon neoadjuvant chemotherapy (NAC) have improved prognosis. Molecular subtypes of bladder cancer differ markedly regarding sensitivity to cisplatin-based chemotherapy and harbor FGFR treatment targets...

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Detalles Bibliográficos
Autores principales: Ecke, Thorsten H., Voß, Paula Carolin, Schlomm, Thorsten, Rabien, Anja, Friedersdorff, Frank, Barski, Dimitri, Otto, Thomas, Waldner, Michael, Veltrup, Elke, Linden, Friederike, Hake, Roland, Eidt, Sebastian, Roggisch, Jenny, Heidenreich, Axel, Rieger, Constantin, Kastner, Lucas, Hallmann, Steffen, Koch, Stefan, Wirtz, Ralph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323197/
https://www.ncbi.nlm.nih.gov/pubmed/35887247
http://dx.doi.org/10.3390/ijms23147898