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Functional Expression of Multidrug-Resistance (MDR) Transporters in Developing Human Fetal Brain Endothelial Cells

There is little information about the functional expression of the multidrug resistance (MDR) transporters P-glycoprotein (P-gp, encoded by ABCB1) and breast cancer resistance protein (BCRP/ABCG2) in the developing blood–brain barrier (BBB). We isolated and cultured primary human fetal brain endothe...

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Detalles Bibliográficos
Autores principales: Lye, Phetcharawan, Bloise, Enrrico, Imperio, Guinever E., Chitayat, David, Matthews, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323234/
https://www.ncbi.nlm.nih.gov/pubmed/35883702
http://dx.doi.org/10.3390/cells11142259