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Antifibrotic preventive effect of polyethylene glycol (PEG) 3350 in methotrexateinduced hepatoxicity model

PURPOSE: Liver damage caused by drugs and other chemicals accounts for about 5% of all cases. Methotrexate (MTX), a folic acid analogue, is a first-line synthetic antimetabolite agent routinely used in the treatment of rheumatoid arthritis and other autoimmune and chronic inflammatory diseases. Poly...

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Detalles Bibliográficos
Autores principales: Acar, Hüseyin, Sorgun, Omay, Yurtseve, Güner, Bora, Ejder Saylav, Erbaş, Oytun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323303/
https://www.ncbi.nlm.nih.gov/pubmed/35894304
http://dx.doi.org/10.1590/acb370507