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Antifibrotic preventive effect of polyethylene glycol (PEG) 3350 in methotrexateinduced hepatoxicity model
PURPOSE: Liver damage caused by drugs and other chemicals accounts for about 5% of all cases. Methotrexate (MTX), a folic acid analogue, is a first-line synthetic antimetabolite agent routinely used in the treatment of rheumatoid arthritis and other autoimmune and chronic inflammatory diseases. Poly...
Autores principales: | Acar, Hüseyin, Sorgun, Omay, Yurtseve, Güner, Bora, Ejder Saylav, Erbaş, Oytun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323303/ https://www.ncbi.nlm.nih.gov/pubmed/35894304 http://dx.doi.org/10.1590/acb370507 |
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