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Dynamic Interactions of Post Cleaved NS2B Cofactor and NS3 Protease Identified by Integrative Structural Approaches

Diseases caused by flaviviruses such as dengue virus (DENV) and West Nile Virus (WNV), are a serious threat to public health. The flavivirus single-stranded RNA genome is translated into a polyprotein which is cleaved into three structural proteins and seven non-structural proteins by the viral and...

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Detalles Bibliográficos
Autores principales: Quek, Jun-Ping, Ser, Zheng, Chew, Bing Liang Alvin, Li, Xin, Wang, Lili, Sobota, Radoslaw M., Luo, Dahai, Phoo, Wint Wint
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323329/
https://www.ncbi.nlm.nih.gov/pubmed/35891424
http://dx.doi.org/10.3390/v14071440