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Capturing Transitional Pluripotency through Proline Metabolism

In this paper, we summarize the current knowledge of the role of proline metabolism in the control of the identity of Embryonic Stem Cells (ESCs). An imbalance in proline metabolism shifts mouse ESCs toward a stable naïve-to-primed intermediate state of pluripotency. Proline-induced cells (PiCs), al...

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Detalles Bibliográficos
Autores principales: Minchiotti, Gabriella, D’Aniello, Cristina, Fico, Annalisa, De Cesare, Dario, Patriarca, Eduardo Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9323356/
https://www.ncbi.nlm.nih.gov/pubmed/35883568
http://dx.doi.org/10.3390/cells11142125